Purushothaman, Gayathri; Thiruvenkatam, Vijay(International Union of Crystallography, 2018-07)
The existence of intermolecular interactions and the conformational geometry adopted by molecules are related to biological activity. Xanthenedione molecules are promising and emerging antioxidants and acetylcholinesterase ...
Background
Alzheimer's disease (AD) is the most common neurodegenerative disorder which is characterized by the deposits of intra-cellular tau protein and extra-cellular amyloid-β (Aβ) peptides in the human brain. ...
Haaland, Kathleen Y.; Dum, Richard P.; Mutha, Pratik K.; Strick, Peter L.; Tröster, Alexander I.(Cambridge University Press, 2018-10)
This paper highlights major developments over the past two to three decades in the neuropsychology of movement and its disorders. We focus on studies in healthy individuals and patients, which have identified cognitive ...
Human Tousled-like kinases (TLKs) are highly conserved serine/threonine protein kinases responsible for cell proliferation, DNA repair, and genome surveillance. Their possible involvement in cancer via efficient DNA repair ...
Designed multi-target ligand (DML) is an emerging strategy for the development of new drugs and involves the engagement of multiple targets with the same moiety. In the context of NSAIDs it has been suggested that targeting ...
Chilka, Pallavi; Pallavi, Patlolla; Reddy, Prathap; Datta, Bhaskar(NISCAIR-CSIR, India, 2018-02)
Food borne toxins represent a serious challenge to the advances in the operation of the food industry with respect to food processing and distribution. While selective identification of the toxins can be easily accomplished ...
Graphene-based nanomaterials (GBNMs) are widely used in various industrial and biomedical applications. GBNMs of different compositions, size and shapes are being introduced without thorough toxicity evaluation due to the ...