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Now showing items 33-52 of 179

Deciphering the GTP binding domain: a python based approach

Sanghavi, Hiral M.; Dasgupta, Anirban; Majumdar, Sharmistha (Centre for Development of Advanced Computing, 2017-01-17)
Degradation of intracellular tau protein isoform using a multifunctional peptide molecule

Gupta, Rahul (Indian Institute of Technology Gandhinagar, 2019)
Design and in Silico Biological evaluations against human Carbonic Anhydrase IX of Novel N-Substituted-?-D-Glucosamine Sulfonylurea and N-Urea Derivatives

Das Mahapatra, Amarjyoti; Datta, Bhaskar (2017-12-18)
Design, synthesis and biological evaluation of Helicobacter pylori inosine 5?-monophosphate dehydrogenase (HpIMPDH) inhibitors. Further optimization of selectivity towards HpIMPDH over human IMPDH2

Shah, Chetan P.; Purushothaman, Gayathri; Thiruvenkatam, Vijay; Kirubakaran, Sivapriya; Juvale, Kapil; Kharkar, Prashant S. (Elsevier, 2019-06)

Inosine 5′-monophosphate dehydrogenase (IMPDH, EC 1.1.1.205) catalyzes a crucial step in guanine nucleotide biosynthesis, thereby governing cell proliferation. In contrast to mammalian IMPDHs, microbial IMPDHs are relatively ...
Design, synthesis and biological evaluation of new phenothiazine derivatives as potential tousled-like kinase 1 inhibitors in prostate cancer treatment

Bhoir, Siddhant; Singh, Vibha; Hussain, Javeena; Chikhale, Rupesh; Bryce, Richard; Kirubakaran, Sivapriya; De Benedetti, Arrigo (2018-03-29)
Design, synthesis and optical characterization Of single fluorophore targeting different sub-cellular regions

Mukherjee, Tarushyam; Soppina, Virupakshi; Kanvah, Sriram (07-02-2019)
Detection of pathological tau conformers in cerebrospinal fluid

Gupta, Sharad et al. (FASEB, 2013-04)

Misfolded tau is a pathological hallmark of over 20 phenotypically distinct neurodegenerative disorders, including Alzheimer's disease (AD). Researchers are beginning to speculate that misfolded tau may spread throughout ...
Determination of data analysis pipeline for ChIP-exo Illumina based data

Sharma, Vasudha; Majumdar, Sharmistha (Centre for Cellular and Molecular Biology, 2017-03-03)
Determination of data analysis pipeline for detection of Thap-9 binding sites in human genome

Sharma, Vasudha; Majumdar, Sharmistha (2017-10-02)
Determination of data analysis pipeline for detection of THAP9 binding sites in human genome

Sharma, Vasudha; Majumdar, Sharmistha (2018-01-27)
Determining the significance of Kinesin-3 family Specific novel motility Outputs in the caenorhabditis elegans axonal transport and function

Soppina, Virupakshi (2016-01)
Development of a low cost EMG devices to display electrical activity of skeletal muscle on a smartphone

Kumar, Sitesh (Indian Institute of Technology Gandhinagar, 2018)
Development of Novel Quinoline based small molecules for targeting the Kinases of the DNA damage and repair pathway

Srimadhavi, Ravi; Sugata, Barui; Kirubakaran, Sivapriya (2018-09-14)
Development of novel quinoline based small molecules for targeting the kinases of the DNA damage and repair pathway

Ravi, Srimadhavi; Barui, Sugata; Kirubakaran, Sivapriya (2018-12-01)
Development of potent and selective inhibitors for ATR: an adjuvant for DNA damage based chemotherapeutics

Shaik, Althaf; Bakuni, Rashmi; Thiruvenkatam, Vijay; Kirubakaran, Sivapriya (American association for cancer research, 2017-04-01)
Dichotomy of carbamylation: A comparison of aggregation propensity of carbamylated alpha-synuclein and fibril core peptides

Gadhavi, Joshna; Gupta, Sharad (2019-10-19)
Dimeric carbocyanine dye and nucleic acid aptamer mediated detection of food borne toxin

Chilka, Pallavi; Pallavi, Patlolla; Reddy, Prathap; Datta, Bhaskar (NISCAIR-CSIR, India, 2018-02)

Food borne toxins represent a serious challenge to the advances in the operation of the food industry with respect to food processing and distribution. While selective identification of the toxins can be easily accomplished ...
Distinct DNA sequence preference for histone occupancy in primary and transformed cells

Datta, Subhamoy; Patel, Manthan; Patel, Divyesh; Singh, Umashankar (SAGE Journals, 2019-04)

Genome-wide occupancy of several histone modifications in various cell types has been studied using chromatin immunoprecipitation (ChIP) sequencing. Histone occupancy depends on DNA sequence features like inter-strand ...
Diverse applications of Nanotechnology in Biomedicine, Chemistry, and Engineering

Kirubakaran, Sivapriya; Thiruvenkatam, Vijay (IGI Global, 2014)

This chapter introduces the basic concepts of nano science to readers. Some novel methodologies for synthesizing nano particles are discussed briefly. Since the book title suggests diverse applications of nano materials, ...
Dynamic bimodal changes in CpG and non-CpG methylation genome-wide upon CGGBP1 loss-of-function

Patel, Divyesh; Patel, Manthan; Westermark, Bengt; Singh, Umashankar (BioMed Central, 2018-07)

Although CpG methylation is well studied, mechanisms of non-CpG methylation in mammals remains elusive. Studying proteins with non-CpG cytosine methylation-sensitive DNA-binding, such as human CGGBP1, can unveil cytosine ...

Now showing items 33-52 of 179

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