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Now showing items 103-122 of 222

Identification of PfENR inhibitors: a hybrid structure?based approach in conjunction with molecular dynamics simulations

Manhas, Anu; Patel, Anjali; Lone, Mohsin Y.; Jha, Prafulla K.; Jha, Prakash C. (Wiley, 2018-08)

In the current study, we have constructed receptor-based pharmacophore models by exploiting the Plasmodium falciparum enoyl-acyl carrier protein reductase (PfENR) structural proteome. The derived models were subjected to ...
Identify and test novel ubiquitin modifier networks in DNA damage signaling and repair process

Kumar, Pabba Maruthi (Indian Institute of Technology Gandhinagar, 2019)
Identifying the Evolutionary Modifications of Superprocessivity in Kinesin-3 Motors

Soppina, Virupakshi; Patel, Nishaben; Mayya, Chaithra (2016-12-14)
An immunochemistry-based screen for chemical inhibitors of DNA-protein interactions and its application to human CGGBP1

Patel, Manthan; Patel, Divyesh; Datta, Subhamoy; Singh, Umashankar (BioMed Central, 2020-12)

Inhibition of DNA-binding of proteins by small-molecule chemicals holds immense potential in manipulating the activities of DNA-binding proteins. Such a chemical inhibition of DNA-binding of proteins can be used to modulate ...
Impact of graphene-based nanomaterials (GBNMs) on the structural and functional conformations of hepcidin peptide

Singh, Krishna P.; Baweja, Lokesh; Wolkenhauer, Olaf; Rahman, Qamar; Gupta, Shailendra K. (Springer Verlag, 2018-03)

Graphene-based nanomaterials (GBNMs) are widely used in various industrial and biomedical applications. GBNMs of different compositions, size and shapes are being introduced without thorough toxicity evaluation due to the ...
IMPDH as a drug target for H. pylori infection: validating zebra fish model

Saxena, Pragati (Indian Institute of Technology Gandhinagar, 2020)
IMPDH as a therapeutic target against H. pylori infection

Purushothaman, Gayathri; Sharma, Gaurav; Menon, Aishwarya; Juvale, Kapil; Thiruvenkatam, Vijay; Kirubakaran, Sivapriya (Indian Institute of Technology Gandhinagar, 2016-12-08)
Improving heterologous expression of tau protein in E.coli and understanding its truncation profile by proteomic approachImproving heterologous expression of tau protein in E.coli and understanding its truncation profile by proteomic approach

Guru, Krishnakumar Viswanathan; Hivare, Pravin; Gupta, Sharad (2018-01-05)
In search of drugs for helicobacter pylori infection

Pamulapati, Sushma Sri; Kirubakaran, Sivapriya; Thiruvenkatam, Vijay (Indian Institute of Technology, Bombay, 2014-03)
Influence of phosphorylation on the foamability and stability of bovine serum albumin and citrus peel pectin mixed foams

Modak, Shrikant; Guru, Krishnakumar Viswanathan; Gupta, Sharad; Thareja, Prachi (Taylor & Francis, 2017-09)

We study the influence of phosphorylation on the foamability and stability of Bovine Serum Albumin (BSA), phosphorylated BSA (pBSA) and citrus peel pectin (CPP) mixed foams as a function of BSA – CPP, pBSA – CPP mixing ...
Influence of polarization on carbohydrate hydration: a comparative study using additive and polarizable force field

Pandey, Poonam; Mallajosyula, Sairam Swaroop (2016-11-14)
The influence of visual target information on the online control of movements

Sarlegna, Fabrice R.; Mutha, Pratik K. (Elsevier, 2015-05)

The continuously changing properties of our environment require constant monitoring of our actions and updating of our motor commands based on the task goals. Such updating relies upon our predictions about the sensory ...
Inhibition of ?-synuclein fibrillogenesis by diphenyl triazine hybrids: design, synthesis and in-vitro efficacy studies

Gadhavi, Joshna; Maqbool, Mudasir; Hivare, Pravin; Gupta, Sharad; Hoda, Nasimul (2020-12-02)
Inhibitor peptide design for TAU protein aggregation

Pandey, Poonam; Gupta, Sharad (2014-02-08)
An insight of scientific developments in TSC for better therapeutic strategy

Natarajan, Nalini; Thiruvenkatam, Vijay (Bentham Science Publishers, 2020-08)

Tuberous sclerosis complex (TSC) is a rare genetic disease, which is characterized by non-cancerous tumors in multi-organ systems in the body. Mutations in the TSC1 or TSC2 genes are known to cause the disease. The resultant ...
Insilico characterization of gamma secretase activating protein (GSAP) and its involvement in alzheimer's disease

Meheta, Kapilkumar (Indian Institute of Technology Gandhinagar, 2019)
Integrating in vitro and in silico approaches to evaluate the "dual functionality" of palmatine chloride in inhibiting and disassembling Tau-derived VQIVYK peptide fibrils

Haja, Esraa; Loseva, Yelena; Guru, Krishnakumar Viswanathan; Pichinuk, Edward; Engel, Hamutal; Raveh, Avi; Gazit, Ehud; Segal, Daniel (Elsevier, 2018-04)

Background Alzheimer's disease (AD) is the most common neurodegenerative disorder which is characterized by the deposits of intra-cellular tau protein and extra-cellular amyloid-β (Aβ) peptides in the human brain. ...
Interaction of a dimeric carbocyanine dye aggregate with bovine serum albumin in non-aggregated and aggregated forms

Reddy Patlolla, Prathap; Desai, Nakshi Nayan; Gupta, Sharad; Datta, Bhaskar (Elsevier, 2018-10)

The interaction of fluorescent dyes with serum proteins has garnered significant interest owing to potential for non-covalent labeling and imaging applications. In this work, dimeric benzothiazole-based trimethine cyanine ...
Interaction of dimeric carbocyanine dye with G-rich DNA

Chilka, Pallavi (Indian Institute of Technology Gandhinagar, 2019)
The interaction of flavonols with membrane components: potential effect on antioxidant activity

Saha, Sarmistha; Panieri, Emiliano; Suzen, Sibel; Saso, Luciano (Springer Verlag, 2020-02)

Flavonols are the most widely distributed class of dietary flavonoids with a wide range of pharmacological properties due to their potent lipid peroxidation inhibition activity. The permeability and orientation of these ...

Now showing items 103-122 of 222

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