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Now showing items 115-134 of 179

Mapping the processivity determinants of the Kinesin-3 motor domain

Scarabelli, Guido; Soppina, Virupakshi; Yao, Xin-Qiu; Atherton, Joseph; Moores, Carolyn A.; Verhey, Kristen J.; Grant, Barry J. (Elsevier, 2016-02)
MDC1 depletion promotes cisplatin induced cell death in cervical cancer cells

Singh, Neeru; Bhakuni, Rashmi; Chhabria, Dimple; Kirubakaran, Sivapriya (BMC, 2020-03)
Mechanism of bovine serum albumin aggregation under reduced environment

Hivare, Pravin; Guru, Krishnakumar Viswanathan; Gupta, Sharad (2019-03-08)
Mechanistic insights into remodeled Tau-derived PHF6 peptide fibrils by Naphthoquinone-Tryptophan hybrids

Guru, Krishnakumar Viswanathan; Paul, Ashim; Segal, Daniel (Nature Publishing Group, 2018-01)

Intra-cellular tau protein tangles and extra-cellular ?-amyloid plaques are hallmarks of Alzheimer's disease (AD), characterized by the conversion of natively unfolded monomeric protein/peptide into misfolded ?-sheet rich ...
Mechanistic study of HpIMPDH by Mutational studies

Menon, Aishwarya; Purushothaman, Gayathri; Sharma, Gaurav; Kirubakaran, Sivapriya; Thiruvenkatam, Vijay (2018-09-14)
Molecular cloning and expression analysis of Human TLK1B-Kinase Domain construct in Escherichia coli

Raman, Shashank; Bhoir, Siddhant; Kirubakaran, Sivapriya (2018-01-04)
Molecular cloning, expression and purification of human tousled like kinase 1B kinase domain (hTLK1B_KD) construct in escherichia coli

Raman, Shashank (Indian Institute of Technology Gandhinagar, 2018)
Molecular docking, molecular modeling, and molecular dynamics studies of azaisoflavone as dual COX-2 inhibitors and TP receptor antagonists

Hadianawala, Murtuza; Mahapatra, Amarjyoti Das; Yadav, Jitender K.; Datta, Bhaskar (Springer Verlag, 2018-03)

Designed multi-target ligand (DML) is an emerging strategy for the development of new drugs and involves the engagement of multiple targets with the same moiety. In the context of NSAIDs it has been suggested that targeting ...
Molecular mechanism of Rab22a mediated regulation of KIF13A motility and cargo recycling

Patel, Nishaben; Sharma, Prerna; Kumari, Ruchi; Siva, Aravintha; Setty, Subba Rao; Soppina, Virupakshi (Biophysical Society, 2020-02)
Motor Adaptation Deficits in Ideomotor Apraxia

Mutha, Pratik K.; Stapp, Lee H.; Sainburg, Robert L.; Haaland, Kathleen Y. (Cambridge University Press, 2017-02)

Objectives: The cardinal motor deficits seen in ideomotor limb apraxia are thought to arise from damage to internal representations for actions developed through learning and experience. However, whether apraxic patients ...
Motor adaptation deficits in ideomotor apraxia

Mutha, Pratik K.; Stapp, Lee H.; Sainburg, Robert L.; Haaland, Kathleen Y. (Assocition for Cognitive Science, 2014-03-03)
Nanobiocatalyst facilitated aglycosidic quercetin as a potent inhibitor of tau protein aggregation

Kumar, Sanjay; Guru, Krishnakumar Viswanathan; Morya, Vinod; Gupta, Sharad; Datta, Bhaskar (Elsevier, 2019-10)

Polyphenols have been suggested as potential therapeutic agents for the treatment of amyloidogenic diseases. In this work, we evaluate quercetin-rich onion extract for its ability to inhibit tau fibrillization. Considering ...
Neurodegenerative disease mutations in KIF1A motor domain and their effect on motility properties

Shewale, Dipeshwari; Soppina, Virupakshi (23-01-20)
The Neuropsychology of movement and movement disorders: neuroanatomical and cognitive considerations

Haaland, Kathleen Y.; Dum, Richard P.; Mutha, Pratik K.; Strick, Peter L.; Tröster, Alexander I. (Cambridge University Press, 2018-10)

This paper highlights major developments over the past two to three decades in the neuropsychology of movement and its disorders. We focus on studies in healthy individuals and patients, which have identified cognitive ...
A new disaggregation induced emission enhancement (DIEE)based probe for cellular detection of copper and lactate

Gour, Nidhi; Kshtriya, Vivek Shinh; Singh, Dheeraj K.; kanth P., Chandra; Bhatia, Dhiraj (2019-06)

We report self assembling/aggregation properties of acyl-thiourea derivative, N-((6-methoxy-pyridin-2-yl)carbamothioyl)benzamide(NG1) [i1] and the disaggregation induced emission which leads to its application as fluorescence ...
A novel sensor for sequential and cellular detection of copper and lactic acid

Gour, Nidhi; Kharbanda, Sumit; Pandey, Deepak Kumar; Singh, Dheeraj K.; Bhatia, Dhiraj; Kshtriya, Vivek Shinh; Kanth P., Chandra (ChemRxiv.org, 2020-06)
Nucleic acid based nanoconstructs for environmental analysis in atypical contexts

Singhal, Aditi; Kapil, Kriti; Dodla, Ankit; Kumar, Sanjay; Datta, Bhaskar (Springer Nature, 2020)
Nucleic acid enable Nano-biosensor development for the Pathogenic target DNA detection

Kumar, Sanjay; Datta, Bhaskar; Serpe, Michael (2017-08-23)
P Transposable Elements in Drosophila and other Eukaryotic Organisms

Majumdar, Sharmistha; Rio, Donald C. (American Society for Microbiology, 2015-04)

P transposable elements were discovered in Drosophila as the causative agents of a syndrome of genetic traits called hybrid dysgenesis. Hybrid dysgenesis exhibits a unique pattern of maternal inheritance linked to the ...
Packing polymorphs of 4H-pyrido[1,2-a]pyrimidin-4-one derivative, a drug intermediate with anti-proliferative property - a qualitative analysis

Kirubakaran, Sivapriya; Thiruvenkatam, Vijay; Shaik, Althaf; Srimadhavai, R. (Indian Institute of Technology Gandhinagar, 2016-12-08)

Now showing items 115-134 of 179

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