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Now showing items 113-132 of 134

Scrutinizing the oligomerization of transposase and its probable role in transposition

Gupta, Neha; Sanghavi, Hiral M.; Majumdar, Sharmistha (1/27/2018)
Selective G-Quadruplex recognition by a novel cyanine dye

Chilka, Pallavi; Patlolla, Prathap Reddy; Datta, Bhaskar (Albany 2015, 2015-06-19)

G-rich sequences have been the focus of intense investigations into their widespread occurrence in the human genome. The primary motivation behind these investigations is the ability of G-rich sequences to fold into ...
Self-assembled glycosylated chalcone–boronic acid nanodrug exhibits anticancer activity through mitochondrial impairment

Ghosh, Chandramouli; Gupta, Neha; Mallick, Abhik; Santra, Manas Kumar; Basu, Sudipta (ACS Publications, 2018-07)
Separation of staining dyes using nucleic acid-based nano bio-constructs and interplay of quadruplex targeting drugs with quadruplex specific staining dyes

Singhal, Aditi (Indian Institute of Technology Gandhinagar, 2018)
Sequence based design of inhibitor peptides for amyloid beta aggregation

Saha, Sarmistha; Gupta, Sharad (2017-07-28)
Simplified method to obtain enhanced expression of Tau protein from E. coli and one-step purification by direct boiling

Guru, Krishnakumar Viswanathan; Gupta, Sharad (Taylor & Francis, 2017-05)

Tau is an intrinsically disordered protein responsible for maintaining the structure and stability of axonal microtubules. However, in certain disease conditions including Alzheimer's disease, tau protein may undergo ...
Small molecule-mediated imaging of G-quadruplexes to elucidate its biological relevance

Desai, Nakshi Nayan; Chilka, Pallavi; Reddy Patlolla, Prathap; Datta, Bhaskar (2018-01-05)
Strategy for high yield production of human tousled-like Kinase 1B in Escherichia coli

Bhoir, Siddhant; Thiruvenkatam, Vijay; Kirubakaran, Sivapriya (2018-01-27)
Structural and functional characterization of membrane protein CD-151 via X-Ray Crystallography

Purushothaman, Gayathri; Thiruvenkatam, Vijay (Zydus Research Centre, 2017-02-02)
Structural aspects of TSC1/2 complex, a molecular switch controlling various cell signaling pathways

Thiruvenkatam, Vijay; Natarajan, Nalini (Zydus Research Centre, 2017-02-02)
Structural investigation and in-silico characterization of Plasmepsins from Plasmodium falciparum

Nair, Divya N.; Singh, Vijay; Angira, Deekshi; Thiruvenkatam, Vijay (OMICS International, 2016-07)

Malaria is the one most important parasitic disease of humans, which affects approximately one hundred countries and threatens half of the world’s population. The Plasmodium aspartic protease called plasmepsins performs a ...
Structural means of assessing interaction between hamartin and tuberin

Natarajan, Nalini; Thiruvenkatam, Vijay (2017-08-21)

mTOR pathway is one of the most important and well-studied signalling cascades with respect to cancer. The major controllers of mTOR are the tumour suppressors Hamartin (TSC1) and Tuberin (TSC2), which lies in the heart ...
Structural means of assessing the association of hamartin and tuberin

Natarajan, Nalini; Thiruvenkatam, Vijay (International Union of Crystallography, 2017-08)

mTOR pathway is one of the most important and well-studied signalling cascades with respect to cancer. The majorcontrollers of mTOR are the tumour suppressors Hamartin (TSC1) and Tuberin (TSC2), which lies in the heart of ...
Studies on different length of A? and their role in aggregation kinetics

Ghawri, Preetika; Gadhavi, Joshna; Gupta, Sharad (2018-01-06)
Study of interaction of Lasioglossin-III with lipid bilayers by molecular dynamics simulations

Ratrey, Poonam; Saha, Sarmistha; Mishra, Abhijit (2016-12-12)
Studying interactions of hamartin and tuberin at the molecular level

Thiruvenkatam, Vijay; Natarajan, Nalini (Indian Institute of Technology Gandhinagar, 2016-12-08)
Synthesis and characterization of dopamine modified Iron Oxide nanoparticles for biological applications

Ratrey, Poonam; Datta, Bhaskar (IIT-BHU, 2017-02-19)
Tau protein post-translational modification and small molecules interaction: molecular mechanisms of fibrillary assemblies, disassembly and aggregation inhibition

Krishankumar, V Guru (Indian Institute of Technology Gandhinagar, 2018)
Tracing the GSAP-APP C-99 interaction site in the β-amyloid pathway leading to Alzheimer's disease

Angira, Deekshi; Chikhale, Rupesh; Mehta, Kapilkumar; Bryce, Richard A.; Thiruvenkatam, Vijay (American Chemical Society, 2019-07)

Gamma secretase activating protein (GSAP) present in β-amyloid pathway orchestrates the formation of β-amyloid plaques by γ-secretase activation and is an emerging therapeutic target for the treatment of Alzheimer’s disease. ...
A unique, robust and scalable coexpression approach for high yield bacterial production of recombinant Human Tousled-like Kinase 1B involved in cancer

Bhoir, Siddhant; Shaik, Althaf; Thiruvenkatam, Vijay; Kirubakaran, Sivapriya (2018-03-12)

Now showing items 113-132 of 134

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