Shah, Chetan P.; Purushothaman, Gayathri; Thiruvenkatam, Vijay; Kirubakaran, Sivapriya; Juvale, Kapil; Kharkar, Prashant S.
(Elsevier, 2019-06)
Inosine 5′-monophosphate dehydrogenase (IMPDH, EC 1.1.1.205) catalyzes a crucial step in guanine nucleotide biosynthesis, thereby governing cell proliferation. In contrast to mammalian IMPDHs, microbial IMPDHs are relatively ...