DNA-functionalized nanoparticles for targeted biosensing and biological applications

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dc.contributor.author Singh, Udisha
dc.contributor.author Morya, Vinod
dc.contributor.author Rajwar, Anjali
dc.contributor.author Chandrasekaran, Arun Richard
dc.contributor.author Datta, Bhaskar
dc.contributor.author Ghoroi, Chinmay
dc.contributor.author Bhatia, Dhiraj
dc.coverage.spatial United States of America
dc.date.accessioned 2020-12-09T14:01:04Z
dc.date.available 2020-12-09T14:01:04Z
dc.date.issued 2020-12
dc.identifier.citation Singh, Udisha; Morya, Vinod; Rajwar, Anjali; Chandrasekaran, Arun Richard; Datta, Bhaskar; Ghoroi, Chinmay and Bhatia, Dhiraj, “DNA-functionalized nanoparticles for targeted biosensing and biological applications”, ACS Omega, DOI: 10.1021/acsomega.0c03656, vol. 5, no. 48, pp. 30767-30774, Dec. 2020. en_US
dc.identifier.issn 2470-1343
dc.identifier.uri https://doi.org/10.1021/acsomega.0c03656
dc.identifier.uri https://repository.iitgn.ac.in/handle/123456789/6118
dc.description.abstract Nanoscale systems have increasingly been used in biomedical applications, enhancing the demand for the development of biomolecule-functionalized nanoparticles for targeted applications. Such designer nanosystems hold great prospective to refine disease diagnosis and treatment. To completely investigate their potential for bioapplications, nanoparticles must be biocompatible and targetable toward explicit receptors to guarantee particular detecting, imaging, and medication conveyance in complex organic milieus, for example, living cells, tissues, and organisms. We present recent works that explore enhanced biocompatibility and biorecognition of nanoparticles functionalized with DNA and different DNA entities such as aptamers, DNAzymes, and aptazymes. We sum up the methods utilized in the amalgamation of complex nanostructures, survey the significant types of multifunctional nanoparticles that have been developed in the course of recent years, and give a perceptual vision of the significant field of nanomedicine. The field of DNA-functionalized nanoparticles holds an incredible guarantee in rising biomedical zones, for example, multimodal imaging, theranostics, and picture-guided treatments.
dc.description.statementofresponsibility by Udisha Singh, Vinod Morya, Anjali Rajwar, Arun Richard Chandrasekaran, Bhaskar Datta, Chinmay Ghoroi and Dhiraj Bhatia
dc.language.iso en_US en_US
dc.publisher American Chemical Society en_US
dc.subject Functionalization en_US
dc.subject Peptides and proteins en_US
dc.subject Genetics en_US
dc.subject Nanoparticles en_US
dc.subject Cells en_US
dc.title DNA-functionalized nanoparticles for targeted biosensing and biological applications en_US
dc.type Article en_US
dc.relation.journal ACS Omega


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