Dhanka, MukeshMukeshDhankaVithalani, HitashaHitashaVithalaniDave, HarshilHarshilDave2025-08-292025-08-292023-12-22https://repository.iitgn.ac.in/handle/IITG2025/20423The present disclosure relates to a hydrogel flap designed for accelerated wound healing. The hydrogel flap comprises a base material a crosslinking agent that enhances the mechanical strength and stability of the therapeutics-encapsulated hydrogel flap, and an adhesive layer made of poly-methyl vinyl ether-alt-maleic acid (PMVE/MA) integrated into the said base material. The hydrogel flap of the present disclosure further comprises an antibiotic embedded within the base material. The present disclosure also provides a method for its preparation. The hydrogel flap of the present disclosure exhibits enhanced mechanical strength, stretchability, and stability targeted for wounds occurring in dynamic and high-stress-bearing areas of the body. The hydrogel flap has antibacterial properties for infection control and is biodegradable.en-USChemicalPatents Published[202321088094]123456789/11252