Indian Institute of Technology Gandhinagar

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    Publication
    Spotlighting the sensitivities of Hyper-Kamiokande, DUNE and ESSνSB
    (2018-12-01)
    Chakraborty, Kaustav
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    Deepthi, K. N.
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    Goswami, Srubabati
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    Physical Research Laboratory India
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    Physical Research Laboratory India
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    Physical Research Laboratory India
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    Physical Research Laboratory India
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    Indian Institute of Technology Gandhinagar
    Neutrino oscillation physics has entered the precision era and the potential forthcoming experiments Hyper-Kamiokande (T2HK / T2HKK), Deep Under-ground Neutrino Experiment (DUNE) and The European Spallation Source ν-Beam (ESSνSB) project are expected to strengthen this endeavour in the future. In this paper we perform a comprehensive study of the octant, mass hierarchy and CP discovery sensitivities of T2HK / T2HKK, DUNE and ESSνSB project in their individual capacity. We present a comparative account of the probabilities at the respective baselines and explore in detail the physics issues which can cause the differences in the sensitivities among the various experiments. We also find out the optimal exposure required by these experiments for achieving 5σ hierarchy, octant sensitivity and to discover CP violation at 5σ for 60% values of δCP, stand alone and in conjunction with the on going T2K and NOνA experiments. In addition, we study the hierarchy and CP sensitivities of DUNE and T2HK in combination with ESSνSB.
    Scopus© Citations 17
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    Existence of solutions to fully nonlinear elliptic equations with gradient nonlinearity
    (2017-10-01) ;
    Verma, Ram Baran
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    Indian Institute of Technology Gandhinagar
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    Indian Institute of Technology Gandhinagar
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    Indian Institute of Technology Gandhinagar
    In this article, we study the existence and multiplicity of nontrivial solutions to the problem (formula presented) where Ω is a smooth bounded domain in ℝn, n > 2. We show that the problem possesses nontrivial solutions for small value of ε provided f and ψ are continuous and f has a positive zero. We employ degree theory arguments and Liouville type theorem for the multiplicity of the solutionss.
    Scopus© Citations 2
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    Thermodynamic and Kinetic Assessment of Mediated Hydrazine Electro-Oxidation in Nonaqueous Medium
    (2025-08-07)
    Bhavana, R.
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    Negi, Akanksha
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    Indian Institute of Technology Gandhinagar
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    Indian Institute of Technology Gandhinagar
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    Indian Institute of Technology Gandhinagar
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    Indian Institute of Technology Gandhinagar
    Hydrazine oxidation reaction (HzOR) provides an energy-efficient alternative to the oxygen evolution reaction (OER), yielding carbon-free products and minimizing catalyst poisoning. While hydrazine oxidation has been extensively researched in aqueous environments, it remains less explored in organic solvents, and it gains importance because of the recent advancement of ammonia oxidation in nonaqueous media. This study investigates the oxidation of hydrazine in acetonitrile using decamethylferrocene (Fc''), a stable, electron-donating ferrocene derivative. The research focused on reaction kinetics, revealing a first-order dependence on the concentrations of both Fc’’ and hydrazine. Additionally, the impact of pyridine-derived bases on HzOR was examined. Mechanistic insights were developed, and temperature-dependent studies indicated a 4.79 kJ/mol activation barrier for the mediated HzOR. The overpotential for HzOR under the given conditions is found to be 829 mV, which was determined through open-circuit potential (OCP) measurements. Quantitative analyses of the gaseous products were performed, which revealed quantitative hydrogen production. This study significantly adds to the existing literature on HzOR by providing crucial data on its behavior in an organic medium.
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    Neural network based block-level detection of same quality factor double JPEG compression
    (2020-02-01)
    Deshpande, Ajit Umesh
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    Harish, Abhinav Narayan
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    Singh, Shubhranshu
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    Verma, Vinay
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    Khanna, Nitin
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    Indian Institute of Technology Gandhinagar
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    Indian Institute of Technology Gandhinagar
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    Indian Institute of Technology Gandhinagar
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    Indian Institute of Technology Gandhinagar
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    Indian Institute of Technology Gandhinagar
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    Indian Institute of Technology Gandhinagar
    Detecting double JPEG compression with the same quality factor is an open research problem in image forensics. The subtle artifacts of double JPEG compression with the same quantization matrices are often indistinguishable by traditional approaches such as histogram-based feature extraction. Existing approaches fail to effectively classify smaller size patches, due to the absence of sufficient information at smaller scales. To tackle this, we propose a new feature based on the difference of quantized DCT coefficients, which is relatively invariant to the size of the image or image patch. For classification, we utilize the multi-layer-perceptron (MLP) network. We compare our results on multiple patch sizes and quality factors, on the UCID dataset with the existing approaches. Using our proposed feature in conjugation with the existing feature vector along with the use of MLP, we observed a maximum of 1.52% increase in accuracy for smaller sized patches (128 × 128), compressed with a quality factor of 60.
    Scopus© Citations 11
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    Application of Twin-Screw Melt Granulation to Overcome the Poor Tabletability of a High Dose Drug
    (2022-12-01)
    Thakore, Samarth D.
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    Reddy, Katangur Vishruth
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    Dantuluri, Ajay K.
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    Patel, Deepika
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    Kumawat, Akshant
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    Sihorkar, Vaibhav
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    Bansal, Arvind K.
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    National Institute of Pharmaceutical Education and Research, Mohali
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    National Institute of Pharmaceutical Education and Research, Mohali
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    RCC Laboratories India Pvt. Ltd.
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    National Institute of Pharmaceutical Education and Research, Mohali
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    Indian Institute of Technology Gandhinagar
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    RCC Laboratories India Pvt. Ltd.
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    Indian Institute of Technology Gandhinagar
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    National Institute of Pharmaceutical Education and Research, Mohali
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    Indian Institute of Technology Gandhinagar
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    National Institute of Pharmaceutical Education and Research, Mohali
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    Sai Life Sciences Ltd.
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    RCC Laboratories India Pvt. Ltd.
    Pharmaceutical tablet manufacturing has seen a paradigm shift toward continuous manufacturing and twin-screw granulation-based technologies have catalyzed this shift. Twin-screw granulator can simultaneously perform unit operations like mixing, granulation, and drying of the granules. The present study investigates the impact of polymer concentration and processing parameters of twin-screw melt granulation, on flow properties and compaction characteristics of a model drug having high dose and poor tabletability. Acetaminophen (AAP) and polyvinylpyrrolidone vinyl acetate (PVPVA) were used as a model drug (90–95% w/w) and polymeric binder (5–10%w/w), respectively, for the current study. Feed rate (~650–1150 g/h), extruder screw speed (150–300 rpm), and temperature (60–150°C) were used as processing variables. Results showed the reduction in particle size of drug in the extrudates (D90 of 15–25 μm from ~80 μm), irrespective of processing condition, while flow properties were a function of polymer concentration. Overall, good flowability of the products and their tablets with optimum tensile strength can be obtained through using high polymer concentration (i.e., 10% w/w), lower feed rate (~650 g/h), lower extruder screw speed (150 rpm), and higher processing temperatures (up to 120°C). The findings from the current study can be useful for continuous manufacturing of tablets of high dose drugs with minimal excipient loading in the final dosage form.
    Scopus© Citations 6