Short and effective asymmetric synthesis towards alky-lated paraconic acids through organocatalysis

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dc.contributor.advisor Appayee, Chandrakumar
dc.contributor.author Kumar, Amit
dc.date.accessioned 2017-04-07T11:36:50Z
dc.date.available 2017-04-07T11:36:50Z
dc.date.issued 2016
dc.identifier.citation Kumar, A. (2016). Short and effective asymmetric synthesis towards alky-lated paraconic acids through organocatalysis, pp. 23. (Acc.No: T00198) en_US
dc.identifier.uri https://repository.iitgn.ac.in/handle/123456789/2835
dc.description.abstract We report a concise method for the formal synthesis of trisubstituted γ-butyrolactone by cross aldol reaction of commercial available aldehyde and -chlorohexanal in presence of chiral amino acid based organocatalyst. We have synthesized -chlorohexanal by -chlorination of hexanal by using a chiral catalyst. After three steps, we will reach to our final goal which is the biologically active (-)-Phaseolinic acid. We had started our synthesis from γ-butyrolactone which is very cheap and easily available. en_US
dc.description.statementofresponsibility by Amit Kumar
dc.format.extent 23 cm.; ill.; 30 cm+
dc.language.iso en_US en_US
dc.publisher Indian Institute of Technology Gandhinagar en_US
dc.title Short and effective asymmetric synthesis towards alky-lated paraconic acids through organocatalysis en_US
dc.type Thesis en_US
dc.contributor.department Chemistry
dc.description.degree M.Sc.


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