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  • Hadianawala, Murtuza; Datta, Bhaskar (Royal Society of Chemistry, 2016-01)
    Sulfonamide derivatives are an important class of zinc metalloenzyme inhibitors. While the sulfonylurea group is a bioisoster of sulfonamide, their effect on the modulation of metalloenzymes has never been studied. In the ...
  • Chilka, Pallavi; Phillips, Sarah; Datta, Bhaskar (Science Direct, 2015-08)
    Enzyme-mediated polymerization reactions have been widely studied in the context of DNA template-assisted reactions. We have recently highlighted the ability of DNA templates to modulate enzyme-catalyzed single-step ...
  • Idrees, Danish; Hadianawala, Murtuza; Mahapatra, Amarjyoti Das; Datta, Bhaskar; Roy, Sonam; Ahamad, Shahzaib; Khan, Parvez; Hassan, Md. Imtiyaz (Elsevier, 2018-04)
    Selective carbonic anhydrase (CA) inhibitors have gained a lot of importance owing to the implication of specific isoforms of CA in certain diseases like glaucoma, leukemia, cystic fibrosis, and epilepsy. A novel class of ...
  • Ghosh Datta, Shohini; Reynolds, Christopher; Datta, Bhaskar; Goud, Yugender K. (Taylor & Francis, 2014-07)
    The oxazole homodimer YOYO-1 has served as a valuable tool for the detection and quantification of nucleic acids. While the base specificity and selectivity of binding of YOYO-1 has been researched to some extent, the ...
  • Sarpong, Kwabena; Datta, Bhaskar (Hindawi Publishing Corporation, 2012)
    The binding affinity and specificity of nucleic acid aptamers have made them valuable candidates for use as sensors in diagnostic applications. In particular, chromophore-functionalized aptamers offer a relatively simple ...
  • Chilka, Pallavi; Patlolla, Prathap Reddy; Prathap; Datta, Bhaskar (Royal Society of Chemistry, 2016-09)
    A novel dimeric carbocyanine dye is found to recognise G-quadruplex structures selectively compared to mixed sequence or double-stranded DNA molecules. The dye exhibits a preference for G3-bearing parallel quadruplexes and ...
  • Chilka, Pallavi; Desai, Nakshi; Datta, Bhaskar (2019-01)
    G-quadruplexes have gained prominence over the past two decades for their role in gene regulation, control of anti-tumour activity and ageing. The physiological relevance and significance of these non-canonical structures ...
  • Hadianawala, Murtuza; Shaik, Althaf; Hasija, Nisha; Vasu, Anuji K.; Datta, Bhaskar (Wiley-Blackwell, 2016-07)
    Synthetic methods providing access to sulfonylureas are immensely valuable considering the wide usage of sulfonylurea derivatives as hypoglycemic drugs and herbicides. In this work, the scope of a sodium cyanate mediated ...
  • Reddy Patlolla, Prathap; Mahapatra, Amarjyoti Das; Mallajosyula, Sairam Swaroop; Datta, Bhaskar (Royal Society of Chemistry, 2018-03)
    The self-organization, solvatochromism and biomolecular-interaction of cyanine dyes have been the focus of substantial research. In recent years the DNA templated assembly of cyanine dyes has emphasized the cooperative and ...
  • Reddy Patlolla, Prathap; Mallajosyula, Sairam Swaroop; Datta, Bhaskar (Wiley, 2017-11)
    Symmetrical dicarbocyanine dyes are known to cooperatively assemble on DNA templates. With the goal of developing dyes that are capable of template-free self-assembly, two N-linked dimeric benzothiazole containing pentamethine ...

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