Self-assembly of a benzothiazolone conjugate into panchromatic fluorescent fibres and their application in cellular imaging

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dc.contributor.author Kshtriya, Vivekshinh
dc.contributor.author Koshti, Bharti
dc.contributor.author Gangrade, Ankit
dc.contributor.author Haque, Ashadul
dc.contributor.author Singh, Ramesh
dc.contributor.author Joshi, Khashti Ballabh
dc.contributor.author Bhatia, Dhiraj
dc.contributor.author Gour, Nidhi
dc.coverage.spatial United Kingdom
dc.date.accessioned 2012-10-17T09:59:19Z
dc.date.available 2012-10-17T09:59:19Z
dc.date.issued 2021-08
dc.identifier.citation Kshtriya, Vivekshinh; Koshti, Bharti; Gangrade, Ankit; Haque, Ashadul; Singh, Ramesh; Joshi, Khashti Ballabh; Bhatia, Dhiraj and Gour, Nidhi, “Self-assembly of a benzothiazolone conjugate into panchromatic fluorescent fibres and their application in cellular imaging”, New Journal of Chemistry, DOI: 10.1039/D1NJ03269K, vol. 45, no. 37, pp. 17211-17221, Aug. 2021. en_US
dc.identifier.issn 1144-0546
dc.identifier.issn 1369-9261
dc.identifier.uri http://dx.doi.org/10.1039/D1NJ03269K
dc.identifier.uri https://repository.iitgn.ac.in/handle/123456789/6909
dc.description.abstract We report the synthesis and characterization of the structures formed by self-assembly of 4-chloro-2(3H)-benzothiazolone (CBT) into panchromatic fibres and their application in cellular imaging. The aggregationproperties of the synthesized compound were studied extensively under different solvents and concentrationsand their morphologies examined at a supramolecular level by various microscopic techniques such as atomicforce microscopy (AFM), fluorescence microscopy, and optical microscopy. Interestingly, the self-assembledstructures formed by CBT reveal panchromatic emission properties and show blue, green, and red fluorescenceunder different excitation wavelengths. The mechanism of structure formation of the self-assemblies was studied through different techniques such as concentration-dependent 1H-NMR, ATR-FTIR, UV-visiblespectroscopy, and fluorescence spectroscopy. Finally, the utility of CBT for cell imaging applications wasdemonstrated and it can be noted that CBT was efficiently taken up by mammalian cells and the cells revealedpanchromatic emission in the blue, green, and red channels. The intensities of the fluorescence observed wereblue 4 green 4 red and the dye interestingly does not exhibit any fluorescence quenching
dc.description.statementofresponsibility by Vivekshinh Kshtriya, Bharti Koshti, Ankit Gangrade, Ashadul Haque, Ramesh Singh, Khashti Ballabh Joshi, Dhiraj Bhatia and Nidhi Gour
dc.language.iso en_US en_US
dc.publisher Royal Society of Chemistry en_US
dc.subject Self-assembly en_US
dc.subject Benzothiazolone en_US
dc.subject Panchromatic fluorescent fibres en_US
dc.subject Cellular imaging en_US
dc.title Self-assembly of a benzothiazolone conjugate into panchromatic fluorescent fibres and their application in cellular imaging en_US
dc.type Article en_US
dc.relation.journal New Journal of Chemistry


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