Stress-responsive rhodamine bioconjugates for membrane-potential-independent mitochondrial live-cell imaging and tracking

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dc.contributor.author Mukherjee, Tarushyam
dc.contributor.author Regar, Ramprasad
dc.contributor.author Soppina, Virupakshi
dc.contributor.author Kanvah, Sriram
dc.coverage.spatial United Kingdom
dc.date.accessioned 2021-10-08T05:30:46Z
dc.date.available 2021-10-08T05:30:46Z
dc.date.issued 2021-12
dc.identifier.citation Mukherjee, Tarushyam; Regar, Ramprasad; Soppina, Virupakshi and Kanvah, Sriram, “Stress-responsive rhodamine bioconjugates for membrane-potential-independent mitochondrial live-cell imaging and tracking”, Organic & Biomolecular Chemistry, DOI: 10.1039/D1OB01741A, vol. 19, no. 46, pp. 10090-10096, Dec. 2021. (Cover Page) en_US
dc.identifier.issn 1477-0520
dc.identifier.issn 1477-0539
dc.identifier.uri https://doi.org/10.1039/D1OB01741A
dc.identifier.uri https://repository.iitgn.ac.in/handle/123456789/6951
dc.description.abstract The 'power house' of the cell mitochondria upsurges significant interest in its investigation of imaging and mapping of the physiological processes. By utilizing sterol-modified rhodamine, we have performed live-cell imaging of mitochondria without dependence on membrane potential. The sterol probes are highly biocompatible, and can track the mitochondrial live-cell dynamics in a background free manner with improved brightness and impressive contrast. This is a first attempt to study the stress response using a direct fluorescence readout by bio-conjugates of rhodamine inside mitochondria. The results pave the way for developing different sterol markers for understanding the cellular response and function
dc.description.statementofresponsibility by Tarushyam Mukherjee, Ramprasad Regar, Virupakshi Soppina and Sriram Kanvah
dc.format.extent vol. 19, no. 46, pp. 10090-10096
dc.language.iso en_US en_US
dc.publisher Royal Society of Chemistry en_US
dc.subject Stress-Responsive en_US
dc.subject Mitochondrial Live-Cell en_US
dc.subject Bio-conjugates of rhodamine inside mitochondri en_US
dc.subject Cellular response and function en_US
dc.title Stress-responsive rhodamine bioconjugates for membrane-potential-independent mitochondrial live-cell imaging and tracking en_US
dc.type Article en_US
dc.relation.journal Organic & Biomolecular Chemistry


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