DNA nanotechnology-based supramolecular assemblies for targeted biomedical applications

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dc.contributor.author Singh, Ankur
dc.contributor.author Bhatia, Dhiraj
dc.coverage.spatial United States of America
dc.date.accessioned 2022-05-19T13:01:26Z
dc.date.available 2022-05-19T13:01:26Z
dc.date.issued 2022-05
dc.identifier.citation Singh, Ankur and Bhatia, Dhiraj, "DNA nanotechnology-based supramolecular assemblies for targeted biomedical applications", The Chemical Record, DOI: 10.1002/tcr.202200048, May 2022. en_US
dc.identifier.issn 1527-8999
dc.identifier.issn 1528-0691
dc.identifier.uri https://doi.org/10.1002/tcr.202200048
dc.identifier.uri https://repository.iitgn.ac.in/handle/123456789/7747
dc.description.abstract DNA is a polyanionic, hydrophilic, and natural biopolymer that offers properties such as biodegradability, biocompatibility, non-toxicity, and non-immunogenicity. These properties of DNA as an ideal biopolymer offer modern-day researchers' reasons to exploit these to form high-order supramolecular assemblies. These structures could range from simple to complex and provide various applications. Among them, supramolecular assemblies like DNA hydrogels (DNA-HG) and DNA dendrimers (DNA-DS) show massive growth potential in the areas of biomedical applications such as cell biology, medical stream, molecular biology, pharmacology, and healthcare product manufacturing. The application of both of these assemblies has seen enormous growth in recent years. In this focused review on DNA-based supramolecular assemblies like hydrogels and dendrimers, we present the principles of synthesis and characterization, key developments with examples and applications, and conclude with a brief perspective on challenges and future outlook for such devices and their subsequent applications.
dc.description.statementofresponsibility by Ankur Singh and Dhiraj Bhatia
dc.language.iso en_US en_US
dc.publisher Wiley en_US
dc.subject DNA en_US
dc.subject Natural biopolymer en_US
dc.subject Supramolecular assemblies en_US
dc.subject Pharmacology en_US
dc.subject DNA dendrimers en_US
dc.title DNA nanotechnology-based supramolecular assemblies for targeted biomedical applications en_US
dc.type Article en_US
dc.relation.journal The Chemical Record

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