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Unveiling new therapeutic candidates for dystrophinopathies: computational insights into FBXO32 and CD4 modulation

Trivedi, Pooja; Dixit, Nandan; Patel, Saumya; Gupta, Sharad; Sindhav, Gaurang (Springer, 2025-12)

Duchenne Muscular Dystrophy (DMD) and its allelic counterpart, Becker Muscular Dystrophy (BMD), are rare, severe, and prevalent neuromuscular conditions, collectively termed dystrophinopathies. They result from variants ...
Unveiling antidiabetic and antioxidant activities of biogenically synthesized red fluorescent graphene quantum dots using Bauhinia variegata L. leaves

Kadyan, Pooja; Saini, Jaya; Singh, Parul; Arasu, Ponnusamy Thillai; Kataria, Sudhir Kumar (Springer, 2025-12)

In recent years, the utilization of green synthesis routes for the production of nanomaterials has garnered considerable attention owing to their eco-friendly nature and multifaceted applications. Present study presents ...
The role of time spent in unpaid domestic work on educational outcomes among adolescents and young adults: quantitative evidence from India

Sharma, Anupam Joya; Shah, Ankita (Springer, 2025-12)

Higher education among youth is crucial for India’s socio-economic development. Despite policy efforts, challenges persist in retaining students beyond elementary school and improving inclusivity and education quality. ...
The cost and complexity of minimizing envy in house allocation

Madathil, Jayakrishnan; Misra, Neeldhara; Sethia, Aditi (Springer, 2025-12)

We study almost envy-freeness in house allocation, where m houses are to be allocated among n agents so that every agent receives exactly one house. An envy-free allocation need not exist, and therefore we may have to ...
Synergistic deployment of green infrastructure and reflective pavements for mitigation of UHI within urban blocks

Nagar, Chirag; Verma, Shubham Kumar; Sen, Sushobhan (Springer, 2025-12)

Urbanisation is increasing globally, leading to the Urban Heat Island (UHI) effect, where urban areas experience higher temperatures than nearby rural regions. Mitigating UHI is a significant challenge with far-reaching ...
Pharmacomodulation of G-quadruplexes in long non-coding RNAs dysregulated in colorectal cancer

Sharma, Shubham; Mitteaux, Jérémie; Pipier, Angélique; Pirrotta, Marc; Penouilh, Marie-José; Monchaud, David; Datta, Bhaskar (BioMed Central, 2025-12)

Background: Non-coding RNAs (ncRNAs) in human cells constitute a substantial portion of the transcriptome but do not lead to protein synthesis. Among them, long non-coding RNAs (lncRNAs, > 200 nucleotides long) are fascinating ...
Participation of host cell proteins in inclusion bodies of non-segmented RNA virus infected cells: a molecular insight

Sarkar, Sharmistha; Biligiri, Kriti Kestur; Vats, Nisha; Rampalli, Shravanti; Ganguly, Surajit; Kumar, Naveen; Sarkar, Debi Prasad; Ganguly, Nirmal Kumar; Sharma, Nishi Raj (BioMed Central, 2025-12)

Negative-sense RNA viruses (NSVs) carrying a non-segmented genome encompass a broad group of viruses responsible for numerous human diseases such as rabies, mumps, measles, respiratory illness and encephalitis. Viruses ...
Imprint of a quasi-16-day period in boreal summer through modulation of quasi-2-day wave implying interhemispheric coupling

Mitra, Gourav; Guharay, Amitava; Batista, P. P.; Buriti, R. A.; Renkwitz, Toralf; Conte, J. F. (Nature Research, 2025-12)

An interesting case of quasi-2-day wave (Q2DW) amplitude modulation with a quasi-16-day period is investigated using meteor radar winds and global reanalysis data during the 2019 boreal summer. The modulation is found to ...
Highly active brookite titania nanoparticles for degradation of toxic organic pollutants

Mittireddi, Ravi Teja; Dotiyal, Mayank; Roy, Remiya; Prajapati, Deepak; Pandey, Pramina Kumari; Mishra, Abhijit; Panda, Emila (Elsevier, 2025-12)

The degradation of toxic organic pollutants in water bodies through affordable photocatalytic materials is vital in recent times, as their presence can greatly harm both the aquatic and human biospheres. In this regard, ...
Evaluating pre-trained large language models on zero shot prompts for parallelization of source code

Yadav, Devansh; Mondal, Shouvick (Elsevier, 2025-12)

Large Language Models (LLMs) have become prominent in the software development life cycle, yet the generation of performant source code, particularly through automatic parallelization, remains underexplored. This study ...
Coordinating monetary contributions in participatory budgeting

Aziz, Haris; Gujar, Sujit; Padala, Manisha; Suzuki, Mashbat; Vollen, Jeremy (Springer, 2025-12)

We formalize a framework for coordinating funding and selecting projects, the costs of which are shared among agents with quasi-linear utility functions and individual budgets. Our model contains the discrete participatory ...
Annexin-derived self-assembling peptide nanostructures for alleviation of calcium oxalate-induced renal injury

Saha, Sarmistha; Mishra, Abhijit (Springer, 2025-12)

The formation of polycrystalline aggregates in the glomerulus or other components of the urinary system is indisputably the most critical step in the formation of kidney stones and calcium oxalate monohydrate (CaC2O4·H2O) ...
A dataset curated for the assessment of G4s in the LncRNAs dysregulated in various human cancers

Sharma, Shubham; Hassan, Muhammad Yusuf; Barbhuiya, Noman Hanif; Ramolia, Harshit; Shukla, Chinmayee; Singh, Deepshikha; Datta, Bhaskar (Nature Research, 2025-12)

Dysregulated expression of long non-coding RNAs (lncRNAs) in cancer contributes to various hallmarks of the disease, presenting novel opportunities for diagnosis and therapy. G-quadruplexes (G4s) within lncRNAs have gained ...

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