Stable isotope labeling of metal/metal oxide nanomaterials for environmental and biological tracing

Show simple item record

dc.contributor.author Zhang, Peng
dc.contributor.author Misra, Superb
dc.contributor.author Guo, Zhiling
dc.contributor.author Rehkamper, Mark
dc.contributor.author Valsami-Jones, Eugenia
dc.date.accessioned 2019-09-25T12:21:58Z
dc.date.available 2019-09-25T12:21:58Z
dc.date.issued 2019-09
dc.identifier.citation Zhang, Peng; Misra, Superb; Guo, Zhiling; Rehk�mper, Mark and Valsami-Jones, Eugenia, "Stable isotope labeling of metal/metal oxide nanomaterials for environmental and biological tracing", Nature Protocols, DOI: 10.1038/s41596-019-0205-z, Sep. 2019. en_US
dc.identifier.issn 1754-2189
dc.identifier.issn 1750-2799
dc.identifier.uri https://doi.org/10.1038/s41596-019-0205-z
dc.identifier.uri https://repository.iitgn.ac.in/handle/123456789/4847
dc.description.abstract Engineered nanomaterials (NMs) are often compositionally indistinguishable from their natural counterparts, and thus their tracking in the environment or within the biota requires the development of appropriate labeling tools. Stable isotope labeling has become a well-established such tool, developed to assign �ownership� or a �source� to engineered NMs, enabling their tracing and quantification, especially in complex environments. A particular methodological challenge for stable isotope labeling is to ensure that the label is traceable in a range of environmental or biological scenarios but does not induce modification of the properties of the NM or lose its signal, thus retaining realism and relevance. This protocol describes a strategy for stable isotope labeling of several widely used metal and metal oxide NMs, namely ZnO, CuO, Ag, and TiO2, using isotopically enriched precursors, namely 67Zn or 68Zn metal, 65CuCl2, 107Ag or 109Ag metal, and 47TiO2 powder. A complete synthesis requires 1�8 d, depending on the type of NM, the precursors used, and the synthesis methods adopted. The physicochemical properties of the labeled particles are determined by optical, diffraction, and spectroscopic techniques for quality control. The procedures for tracing the labels in aquatic (snail and mussel) and terrestrial (earthworm) organisms and for monitoring the environmental transformation of labeled silver (Ag) NMs are also described. We envision that this labeling strategy will be adopted by industry to facilitate applications such as nanosafety assessments before NMs enter the market and environment, as well as for product authentication and tracking.
dc.description.statementofresponsibility by Peng Zhang, Superb Misra, Zhiling Guo, Mark Rehk�mper and Eugenia Valsami-Jones
dc.language.iso en_US en_US
dc.publisher Springer Nature en_US
dc.title Stable isotope labeling of metal/metal oxide nanomaterials for environmental and biological tracing en_US
dc.type Article en_US
dc.relation.journal Nature Protocols


Files in this item

Files Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record

Search Digital Repository


Browse

My Account