Prevalence of antibiotic resistance in the tropical rivers of Sri Lanka and India

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dc.contributor.author Kumar, Manish
dc.contributor.author Sulfikar; Chaminda
dc.contributor.author Tushara; Patel
dc.contributor.author Arbind Kumar
dc.contributor.author Sewwandi, Himaya
dc.contributor.author Mazumder, Payal
dc.contributor.author Joshi, Madhvi
dc.contributor.author Honda, Ryo
dc.date.accessioned 2020-06-29T14:05:31Z
dc.date.available 2020-06-29T14:05:31Z
dc.date.issued 2020-09
dc.identifier.citation Kumar, Manish; Sulfikar; Chaminda, Tushara; Patel, Arbind Kumar; Sewwandi, Himaya; Mazumder, Payal; Joshi, Madhvi and Honda, Ryo , "Prevalence of antibiotic resistance in the tropical rivers of Sri Lanka and India", Environmental Research, DOI: 10.1016/j.envres.2020.109765, vol. 188, Sep. 2020. en_US
dc.identifier.issn 0013-9351
dc.identifier.issn 1096-0953
dc.identifier.uri https://doi.org/10.1016/j.envres.2020.109765
dc.identifier.uri https://repository.iitgn.ac.in/handle/123456789/5507
dc.description.abstract We evaluate the imprints of urbanization, landuse and lifestyle on the prevalence and provenance of antibiotic resistance in the tropical rivers of Sri Lanka (Kelani and Gin) and India (Sabarmati, and Brahmaputra River). The prevalence of E. coli in the Kelani, Sabarmati, and Brahmaputra Rivers was in the range of 10�27, 267�76,600, and <50 CFU ml?1 respectively. Isolated E. coli colonies were subjected to six antibiotics to assess their resistance. We found higher resistance to old generation antibiotics like tetracycline (TC), and sulfamethoxazole (ST) transcends the resistance for fluoroquinolones like norfloxacin (NFX), ciprofloxacin (CIP), and levofloxacin (LVX). Interestingly, both Indian rivers had exhibited relatively higher resistance to TC and ST than the Kelani river or Gin River, implying that the Sri Lankan situation is relatively less critical. At genetic level the resistance for ?-lactams, fluoroquinolones and sulphonamides, were detected in many samples, as reported globally. While the resistance genes for aac-(6�)-1b-cr, qnrS and sul1 were detected in both Sri Lankan and Indian Rivers, blaTEM and ampC were specific to the Indian Rivers only. Decoupling of the prevalence of metal contamination and antibiotic resistance has been noticed in India and Sri Lanka. Study implies that urbanization, landuse, and lifestyle (ULL) are the three most critical factors governing multidrug resistance (MDR) and fecal contamination.
dc.description.statementofresponsibility by Manish Kumar, Sulfikar, Tushara Chaminda, Arbind K. Patel, Himaya Sewwandi, Payal Mazumder, Madhvi Joshi and Ryo Honda
dc.language.iso en_US en_US
dc.publisher Elsevier en_US
dc.subject Drug-resistance en_US
dc.subject E. coli en_US
dc.subject Resistant genes en_US
dc.subject Kelani river en_US
dc.subject Sri LankaIndia en_US
dc.title Prevalence of antibiotic resistance in the tropical rivers of Sri Lanka and India en_US
dc.type Article en_US
dc.relation.journal Environmental Research


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