Indian Institute of Technology Gandhinagar

Knowledge Repository

Photo by @inspiredimages
Recent Additions
  • Some of the metrics are blocked by your 
    Publication
    IndIGO-D: probing compact binary coalescences in the Decihertz GW Band
    (Cornell University Library, 2026-01-01)
    Sharma, Abhishek
    ;
    Tahelyani, Divya
    ;
    ;
    Mitra, Sanjit
    We study IndIGO-D, a decihertz gravitational-wave mission concept, focusing on a specific configuration in which three spacecraft fly in formation to form an L-shaped interferometer in a heliocentric orbit. The two orthogonal arms share a common vertex, providing a space-based analogue of terrestrial Michelson detectors, while operating in an optimised configuration that yields ppm-level arm-length stability. Assuming 1000 km arm length, we analyse the orbital motion and antenna response, and assess sensitivity across the [0.1 - 10] Hz band bridging LISA and next-generation ground-based interferometers. Using fiducial sensitivity curves provided by the IndIGO-D collaboration, we compute horizon distances for different source classes. Intermediate-mass black-hole binaries with masses 10^{2} - 10^{3} \, M_\odot are detectable to redshifts z \sim 10^{3}, complementing the reach of LISA and terrestrial detectors. Binary neutron star systems are observable to a horizon distance of z \lesssim 0.3, allowing continuous multi-band coverage with Voyager-class interferometers from the decihertz regime to merger. A Bayesian parameter-estimation study of a GW170817-like binary shows that the sky localization area improves from \sim 21 \,\mathrm{deg}^2 at one month to 0.3 \,\mathrm{deg}^2 at six hours pre-merger! These sky areas are readily tiled by wide-field time-domain telescopes such as the Rubin Observatory, whose 9.6 \,\mathrm{deg}^2 field of view and r-band depth enable high-cadence, repeated coverage of GW170817-like kilonovae at this distance and beyond. IndIGO-D exploits the rapid evolution of binaries in the decihertz band to bridge the gap between millihertz and terrestrial observations, enabling early warnings on timescales from months to hours and enhancing the prospects for multi-band and multi-messenger discoveries.
  • Some of the metrics are blocked by your 
    Publication
    Performance Review of The Caretaker: A Play directed by Arindam Mukherjee and Madhurima Goswami. Bengali translation by Anya Theater, Gyan Mancha, Kolkata, India. Staged June 2025
    (Pen State University Press, 2025-12-01)
    Sitting in a packed Gyan Mancha auditorium in Kolkata as Harold Pinter’s work made a comeback in Bengali theater, I was transported to a similar evening two decades ago when soon after his Nobel Prize–winning (2005) The Homecoming was staged at the same venue in English. There have been very few Pinter productions in Bengali theater. Directed by Arindam Mukherjee and Madhurima Goswami and produced by Anya Theater, Caretaker (the definite article dropped from the English title to make it sound colloquial in Bangla) breaks that 20-year silence. The production has a stellar cast with two of the finest contemporary Bengali theater and film actors—Anirban Chakrabarti and Debesh Roy Chowdhuri—essaying Aston (changed to Shankar) and Davies (changed to Adhir) and Tathagata Chowdhury playing Mick, in this version Shankar’s younger brother Tegra.
  • Some of the metrics are blocked by your 
    Publication
    Elucidating the mechanism of Fulvic acid-mediated PCR inhibition and its mitigation through nanoparticle-assisted amplification
    (Elsevier, 2026-01-01)
    Vajpayee, Kamayani
    ;
    Srivastava, Shriyansh
    ;
    Sharma, Shivkant
    ;
    Gupta, Swadha
    ;
    ;
    Paida, Vidhi
    ;
    Dash, Hirak Ranjan
    ;
    Pappachan, Anju
    ;
    Shukla, Ritesh K.
    ;
    Sengupta, Souvik
    Fulvic acid is a common humic contaminant found in soil-matrix forensic samples and is a highly effective PCR inhibitor. This work uses computational analysis to investigate its molecular interaction with Taq DNA polymerase and evaluate nanoparticle-based facilitation strategies. Molecular docking and molecular dynamics simulations proposed selective binding of fulvic acid with catalytic residues (ARG587, ASP610, PHE667, TYR671, ASP785, GLU786), affecting DNA binding, active-site geometry, and Mg²⁺ coordination. Tryptophan quenching assays confirmed a low-affinity (∼251.6 ± 2.2 µM), reversible interaction. Functionally, fulvic acid reduced the peak height by > 80 % within the DNA profile and affected critical loci-D18S51, Penta D, D22S1045, FGA, CSF1PO, and D21S11. Nano-based facilitators-bare and BSA-coated AuNPs-were compared with the commonly employed BSA; the latter showed a statistically significant (p < 0.0001) 25 % TPH improvement compared to the inhibited level but did not affect allelic balance. These findings establish the inhibitory mode for fulvic acid and confirm the effectiveness of BSA-coated AuNPs as a scalable solution to restore PCR efficiency to environmentally compromised forensic DNA samples over highly concentrated application of BSA as a facilitator.
  • Some of the metrics are blocked by your 
    Publication
    Explicit reward stabilizes motor output by attenuating sensory prediction error driven learning
    (Cold Spring Harbor Laboratory, 2026-01-01)
    Panthi, Gaurav
    ;
    Motor adaptation driven by sensory prediction errors (SPEs) is often regarded as an automatic, implicit process that operates independent of reward. However, in most past work, reward and performance outcomes (success / failure) have been intrinsically confounded, making it unclear whether explicitly delivered reward per se influences SPE-driven learning. Here, we used an error-clamp paradigm to dissociate reward from both error and task outcome, enabling us to directly test whether explicit reward modulates implicit adaptation. Participants performed reaching movements under clamped visual feedback that produced a constant SPE, while being instructed to ignore the cursor. In two experiments, reward was delivered when the unseen hand successfully intersected the reach target. In an eight-target task, reward did not alter the overall magnitude or time course of adaptation. However, trial-level analyses revealed that rewarded movements were followed by smaller trial-to-trial updates, reduced variability, and a cumulative suppression of adaptive adjustments. Consistent with this result, individuals who experienced reward more frequently exhibited less asymptotic learning. In our second experiment using a simplified, two-target task, these trial-level effects accumulated to produce robust reductions in both asymptotic adaptation and aftereffects in the rewarded groups. Across both experiments, longer streaks of rewarded trials predicted progressively weaker SPE-driven updating. Collectively, these findings demonstrate that implicit adaptation is not insulated from reward signals. Instead, explicit reward appears to attenuate sensitivity to SPEs, stabilizing motor output particularly when the task structure allows consistent action-reward associations. We conclude that motivational signals can gate the expression of error-driven motor adaptation.
  • Some of the metrics are blocked by your 
    Publication
    Spontaneous phase separation enables rapid, polymerization-free fabrication of dissolvable hydrogels
    (Cold Spring Harbor Laboratory, 2026-01-01)
    Priyadarshinee, Namrata
    ;
    Saxena, Vidhi
    ;
    Kambekar, Aniruddha
    ;
    Chauhan, Gaurav
    ;
    Hydrogels are cross-linked polymeric networks with wide applications in drug delivery, tissue engineering, biosensing, and environmental remediation. These hydrogels additionally host living cells, small molecules and biological propagules, which further expand the applications of these materials. However, most if not all fabrication methods require covalent modifications. In this work, for the first time, we demonstrate that polymer mixtures can access an additional material state beyond the conventionally described homogeneous and two-phase regimes. By deliberately selecting polymers with a known propensity to phase separate and formulating compositions far from the binodal boundary, the system transitions directly into a mechanically stable hydrogel. We demonstrate this technique using a model system of poly (ethylene glycol) (PEG) and dextran (DEX). We have systematically characterized the hydrogels through FTIR, MALDI-TOF to discern the molecular compositions of the hydrogels. We also modulate the optical transparency of these hydrogels by varying the molecular weight of the polymers. These experimental findings are supplemented with coarse grained (CG) simulation insights to investigate the mechanistic origins of phase separation propensity with varying molecular weights of dextran. We utilized coexisting densities in the two phases using CG simulations to predict the role of dextran molecular weight on the partitioning of PEG and DEX in the two phases. Finally, we exploit the fabricated hydrogel’s ability to encapsulate live cells, antibiotics and plant seeds. We anticipate that this ATPS-based fabrication technique will provides a scalable, crosslinker-free route to multifunctional hydrogels enabling advanced applications in drug delivery and responsive materials.
Most viewed
  • Some of the metrics are blocked by your 
    Publication
    Semi-supervised automatic generation of Wikipedia articles for named entities
    (2016-01-01)
    Pochampally, Yashaswi
    ;
    Karlapalem, Kamalakar
    ;
    Yarrabelly, Navya
    ;
    Indian Institute of Technology Hyderabad
    ;
    Indian Institute of Technology Gandhinagar
    ;
    Indian Institute of Technology Hyderabad
    ;
    Indian Institute of Technology Hyderabad
    ;
    Indian Institute of Technology Gandhinagar
    We investigate the automatic generation of Wikipedia articles as an alternative to its manual creation. We propose a framework for creating a Wikipedia article for a named entity which not only looks similar to other Wikipedia articles in its category but also aggregates ihe diverse aspects related to that named entity from the Web. In particular, a semi-supervised method is used for determining the headings and identifying the content for each heading in the Wikipedia article generated. Evaluations show that articles created by our system for categories like actors are more reliable and informative compared to those generated by previous approaches of Wikipedia article automation.
  • Some of the metrics are blocked by your 
    Publication
    Integrating the stanford university unstructured (SU2) code with overset grids
    (2015-01-01)
    Kanoria, A. A.
    ;
    Chandar, D. D.J.
    ;
    Indian Institute of Technology Gandhinagar
    ;
    A-Star, Institute of High Performance Computing
    ;
    A-Star, Institute of High Performance Computing
    ;
    Indian Institute of Technology Gandhinagar
    The Stanford University Unstructured design is a tool for solving multi-disciplinary problems governed by the Partial Differential Equations on general, unstructured grids. The Overset algorithm ‘Overset Parallel Engine for AeRodynamic Applications’ developed at Institute of High Performance Computing, Singapore allows dynamic overset grid capabilities with any number of bodies using parallel processing. This paper presents the coupling of OPERA with SU2 for complex multi- body aerospace problems. The modified software suite is tested for the flow past a three dimensional sphere. The results compared with analytical results support the potential and working of the algorithm compared to a non-overlapping grid. The same problem is analyzed for moving overlapping grid. The velocity contours at different time instance are shown and are found to be continuous across the overlapping grid.
  • Some of the metrics are blocked by your 
    Publication
    Advancing CCS in India: Policy Developments, Funding Mechanisms, and the Potential of Basalt Storage Solutions
    (2025-01-01)
    Kala, S.
    ;
    Lam, Y.
    ;
    Rystad Energy
    ;
    Rystad Energy
    ;
    Indian Institute of Technology Gandhinagar
    ;
    Rystad Energy
    Carbon Capture and Storage (CCS) is crucial for reducing emissions in hard-to-decarbonize sectors such as cement, steel, and power generation. For India, heavily reliant on coal, CCS provides a means to lower emissions while maintaining energy security. While global CCS deployment has gained momentum through policy support and funding, high costs remain a significant challenge. In India, basalt formations, especially in the Deccan Traps, present a promising and cost-effective option for CO2 storage through mineralization. India's CCS policy is still in development, with short-term incentives like carbon credits and potential long-term goals, such as carbon taxes, being considered. To scale CCS, India requires robust funding mechanisms, technological innovation, and large-scale CCS clusters. International collaboration and investment will be essential in addressing financial and technological barriers. With the right infrastructure, research, and policy framework, CCS can become a key component of India's strategy to meet its net-zero target by 2070.
  • Some of the metrics are blocked by your 
    Publication
    Privacy preserving synthetic health data
    (2019-01-01)
    Yale, Andrew
    ;
    Dash, Saloni
    ;
    Dutta, Ritik
    ;
    Guyon, Isabelle
    ;
    Pavao, Adrien
    ;
    Bennett, Kristin P.
    ;
    Rensselaer Polytechnic Institute
    ;
    Birla Institute of Technology and Science, Pilani
    ;
    Indian Institute of Technology Gandhinagar
    ;
    UPSud/INRIA Université Paris
    ;
    UPSud/INRIA Université Paris
    ;
    Rensselaer Polytechnic Institute
    ;
    Rensselaer Polytechnic Institute
    ;
    Birla Institute of Technology and Science, Pilani
    ;
    Indian Institute of Technology Gandhinagar
    ;
    UPSud/INRIA Université Paris
    We examine the feasibility of using synthetic medical data generated by GANs in the classroom, to teach data science in health informatics. We present an end-to-end methodology to retain instructional utility, while preserving privacy to a level, which meets regulatory requirements: (1) a GAN is trained by a certified medical-data security-aware agent, inside a secure environment; (2) the final GAN model is used outside of the secure environment by external users (instructors or researchers) to generate synthetic data. This second step facilitates data handling for external users, by avoiding de-identification, which may require special user training, be costly, and/or cause loss of data fidelity. We benchmark our proposed GAN versus various baseline methods using a novel set of metrics. At equal levels of privacy and utility, GANs provide small footprint models, meeting the desired specifications of our application domain. Data, code, and a challenge that we organized for educational purposes are available.
  • Some of the metrics are blocked by your 
    Publication
    Prefetching in hybrid main memory systems
    (2020-01-01)
    Subisha, V.
    ;
    Gohil, Varun
    ;
    Ujjainkar, Nisarg
    ;
    Awasthi, Manu
    ;
    Indian Institute of Technology Gandhinagar
    ;
    Indian Institute of Technology Gandhinagar
    ;
    Indian Institute of Technology Gandhinagar
    ;
    Ashoka University
    ;
    Indian Institute of Technology Gandhinagar
    ;
    Ashoka University
    The architecture of main memory has experienced a paradigm shift in recent years, with non volatile memory technologies (NVM) like Phase Change Memory (PCM) being incorporated into the hierarchy at the same level as DRAM. This transformation is being carried out by either splitting the memory address across two or more memory technologies, or using a faster technology with higher lifetimes, typically the DRAM, as a cache for the higher capacity, albeit slower main memory made up of a NVM. Design of such hybrid architectures remains an active area of research from the perspective of DRAM-as-a-cache design, since DRAM could quickly become the bottleneck, as cache lookups require multiple accesses for reading tag and data. In this paper, we augment the DRAM-as-a-cache model with a novel DRAM cache prefetcher that builds on state of the art Alloy Cache. The new DRAM cache architecture allows for prefetching data at both cacheline and page granularities from the NVM, and as a result, provides upto a maximum of 2× performance improvement over a state of the art baseline.