• Novel pyrazolo [4, 3-c] quinolin-3-one derivatives as PDE5A inhibitors 

  Shaik, Althaf; Agarwal, Harshit Kumar; Bhakuni, Rashmi; Kirubakaran, Sivapriya (2019-02)

  PDE5A is a phosphodiesterase which specifically hydrolyzes the cGMP to GMP. PDE5A takes part in several physiological and pathological pathways and is considered an important drug target. Currently, PDE5 inhibitors (ex; ...
• Branching effect on triphenylamine-CF3 cyanostilbenes: enhanced emission and aggregation in water 

  Kumari, Beena; Singh, Surya Pratap; Santosh, Ranga; Dutta, Arnab; Mallajosyula, Sairam S.; Ghosal, Subhas; Kanvah, Sriram (Royal Society of Chemistry, 2019-03)

  Six linear and branched ?-cyanostilbene derivatives bearing a triphenylamine donor and an electron withdrawing trifluoromethyl group on the phenyl ring and a cyano acceptor on the double bond were synthesized and examined ...
• Small molecule fluorescent probes for G-Quadruplex visualization as potential cancer theranostic agents 

  Chilka, Pallavi; Desai, Nakshi; Datta, Bhaskar (2019-01)

  G-quadruplexes have gained prominence over the past two decades for their role in gene regulation, control of anti-tumour activity and ageing. The physiological relevance and significance of these non-canonical structures ...
• Polyethylenimine coated graphene-oxide nanoparticles for targeting mitochondria in cancer cells 

  Mallick, Abhik; Nandi, Aditi; Basu, Sudipta (American Chemical Society, 2018-12)

  Mitochondrion, the powerhouse of the cells, controls bioenergetics, biosynthesis, metabolism, and signaling. Consequently, it has become an unorthodox target for cancer therapeutics. However, specific targeting of mitochondria ...
• Emission and color tuning of cyanostilbenes and white light emission 

  Kumari, Beena; Paramasivam, Mahalingavelar; Dutta, Arnab; Kanvah, Sriram (American Chemical Society(ACS), 2018-12)

  White-light-emitting diodes are energy efficiency replacement of conventional lighting sources. Herein, we report the luminescent behavior of three simple cyanostilbenes with triphenylamine-donating groups bearing different ...
• La0.80Sr0.20CoO3 as a noble-metal-free catalyst for the direct oxidation of formic acid under zero applied potential 

  Bisht, Anuj; Pentyala, Phanikumar; Deshpande, Parag A.; Sharma, Sudhanshu (Elsevier, 2019-02)

  Direct oxidation of formic acid to CO2 using noble-metal-free La0.80Sr0.20CoO3 is demonstrated in this study. The catalyst was able to oxidize HCOOH without any externally applied potential. The activity of La0.80Sr0.20CoO3 ...
• Cationic red-emitting probes for the rapid and selective detection of SO2 derivatives in aqueous and cellular environments 

  Jana, Palash; Patel, Nishaben; Soppina, Virupakshi; Kanvah, Sriram (Royal Society of Chemistry (RSC), 2018-12)

  Two water-soluble compounds based on a coumarin–pyridinium scaffold were synthesized for rapid and selective detection of sulfite. The detection strategy is possible through a Michael addition reaction of the sulfite to ...
• Direct formic acid electro-oxidation on Pt Doped and Undoped La1-xSrxCoO3: activity suppression due to proton reduction reaction 

  Bisht, Anuj; Sharma, Sudhanshu (Electrochemical Society (ECS), 2018-10)

  Combustion synthesized Pt-doped and undoped La1-xSrxCoO3 are utilized for formic acid electro-oxidation. Cyclic-voltammetry (CV) during formic acid electro-oxidation demonstrates that the oxidation current initially increases ...
• Boron based nanosheets as reducing templates in aqueous solutions: towards novel nanohybrids with gold nanoparticles and graphene 

  James, Asha Liza; Khandelwal, Shikha; Dutta, Arnab; Jasuja, Kabeer (Royal Society of Chemistry, 2018-10)

  We show that nanosheets obtained by exfoliating magnesium diboride bear an intrinsic ability to elicit chemical reduction of quinone-based molecules. They also reduce gold salt into ultra-small gold nanoparticles and ...
• Evaluation of MBP tagged-hATR kinase domain catalytic activity with p53 Ser-15 phosphorylation 

  Bhakuni, Rashmi; Shaik, Althaf; Kirubakaran, Sivapriya (American Chemical Society, 2018-10)

  DNA damage response (DDR) pathways form an integral part of the body’s repair machinery, and ATR (ataxia-telangiectasia and Rad3-related kinase) protein is one of the key mediators in the DDR pathway that helps in maintaining ...
• Chemical method for evaluating catalytic turnover frequencies (TOF) of moderate to slow H2 oxidation electrocatalysts 

  Dutta, Arnab; Shaw, Wendy J. (American Chemical Society (ACS), 2018-10)

  Hydrogen has emerged as a long-term option for storing energy from renewable resources and has led the scientific community to develop enzyme-inspired catalysts for hydrogen oxidation and production. One of the most ...
• Cationic red emitting fluorophore: a light up NIR fluorescent probe for G4-DNA 

  Kumari, Beena; Yadav, Akanksha; Pany, Sushree P.; P. I., Pradeepkumar; Kanvah, Sriram (Elsevier, 2018-10)

  Guanine (G) quadruplexes (G4) are nucleic acid secondary structures formed by G-rich sequences, which are commonly found in human telomeric and oncogene-promoter regions, and they have emerged as targets for regulation of ...
• In search of the representative pharmacophore hypotheses of the enzymatic proteome of Plasmodium falciparum: a multicomplex-based approach 

  Manhas, Anu; Lone, Mohsin Y.; Jha, Prakash C. (Springer, 2018-10)

  Drug resistance has made malaria an untreatable disease and therefore intensified the need for the development of new drugs and the identification of potential drug targets. In this pursuit, in silico efforts made in the ...
• Microbubble-mediated enhanced delivery of curcumin to cervical cancer cells 

  Upadhyay, Awaneesh; Yagnik, Bhrugu; Desai, Priti; Dalvi, Sameer V. (American Chemical Society (ACS), 2018-10)

  The major bottleneck in the current chemotherapy treatment of cancer is the low bioavailability and high cytotoxicity. Targeted delivery of drug to the cancer cells can reduce the cytotoxicity and increase the bioavailability. ...
• Photophysical studies of pyrenyl cyanostyrenes: effect of trifluoromethyl substitution on gelation 

  Katla, Jagadish Kumar; Ojha, Abhijeet; Nair, Akshay J. M.; Krishnan, Rangan; Kanvah, Sriram (Royal Society of Chemistry (RSC), 2018-10)

  ?-cyanostyrenes bearing planar pyrene unit and electron withdrawing trifluoromethyl units were designed and synthesized. The conformational restriction due to the presence of cyano group on the double bond favor aggregation ...
• Light-controlled in situ bidirectional tuning and monitoring of gold nanorod plasmon via oxidative etching with FeCl3 

  Thambi, Varsha; Kar, Ashish; Ghosh, Piue; Khatua, Saumyakanti (American Chemical Society (ACS), 2018-10)

  We report on light-controlled in situ bidirectional tuning of longitudinal surface plasmon resonance (LSPR) of single gold nanorods via oxidative etching with ferric chloride. By removing the surfactant layer from the ...
• Impact of dense internals on fluid dynamic parameters in bubble column 

  Kalaga, Dinesh V.; Bhusare, Vishal; Pant, H.J.; Joshi, Jyeshtharaj B.; Roy, Shantanu (De Gruyter, 2018-09)

  Industrial gas-liquid processes such as oxidation, hydrogenation, Fischer-Trospch synthesis, liquid-phase methanol synthesis,?and nuclear fission are exothermic in nature; the reactor of choice for such processes is, ...
• Highly regioselective α-alkylation of α,β,γ,δ-unsaturated aldehydes 

  Padmaja, Venkata M. D.; Jangra, Sachin; Appayee, Chandrakumar (Royal Society of Chemistry Publishing, 2018-09)

  The first α-alkylation of α,β,γ,δ-unsaturated aldehydes is achieved under mild reaction conditions. Several α,β,γ,δ-unsaturated aldehydes and diarylcarbinols are successfully tested for the synthesis of MBH-type α-alkylated ...
• Designing electrochemically reversible H2 oxidation and production catalysts 

  Dutta, Arnab; Appel, Aaron M; Shaw, Wendy J. (Nature, 2018-08)

  The most energy-efficient electrocatalysts mediate forward and reverse reactions at high rates with minimal overpotential requirements. Such electrocatalytic reversibility is commonly observed for redox enzymes and is an ...
• One step rapid synthesis of mesoporous high surface area Sn1-xSbxO2: Electrochemical and scanning tunneling spectroscopic studies 

  Vyas, Divya; Singhal, Aditi; Sharma, Sudhanshu (American Chemical Society, 2018-08)

  High surface area nanoparticles of antimony doped tin oxide are synthesized for the first time by one step solution combustion method using tin oxalate and antimony chloride as precursors. The synthesis method is rapid and ...

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