• The endeavours in RAS inhibition the past, present, and future 

  Hussain, Javeena; Kirubakaran, Sivapriya; Ravi, Srimadhavi (Bentham Science Publishers, 2020-09)

  KRAS mutations are known to be the most recurrent gain-of-function changes instigated in patients with cancer. The RAS gene family is often mutated in most of the human cancers and the pursuit of inhibitors that bind to ...
• Core-shell Au@AuAg nano-peanuts for the catalytic reduction of 4-nitrophenol: critical role of hollow interior and broken shell structure 

  Thambi, Varsha; Gautam, Abhay Raj Singh; Khatua, Saumyakanti (Royal Society of Chemistry, 2020-08)

  Bimetallic hollow core-shell nanoparticles have gained immense attention especially, as a high-performance catalyst due to their large surface area and increased number of uncoordinated atoms. But, the synthesis of anisotropic ...
• Characterization of P. aeruginosa glucose 6- phosphate isomerase: a functional insight via in-vitro activity study 

  Angira, Deekshi; Natarajan, Nalini; Dedania, Samir R.; Patel, Darshan H.; Thiruvenkatam, Vijay (Bentham Science Publishers, 2020-08)
• Inducing endoplasmic reticulum stress in cancer cells by graphene oxide-based nanoparticles 

  Pandey, Shalini; Nandi, Aditi; Basu, Sudipta; Ballav, Nirmalya (Royal Society of Chemistry, 2020-08)

  Endoplasmic reticulum is one of the vital organelles primarily involved in protein synthesis, folding, transport and lipid biosynthesis. However, in cancer cells its functions are dysregulated leading to ER stress. ER ...
• Investigating structural aspects of pyridopyrimidinone derivatives, an important precursor in medicinal chemistry 

  Shaik, Althaf; Palaniswamy, Parimaladevi; Thiruvenkatam, Vijay (Elsevier, 2020-08)

  Pyridopyrimidinones are class of heterocyclic compounds which serves as important precursors in organic transformation and medicinal chemistry. In the current work three derivatives of pyrido[1,2-a]pyrimidine-3-carboxylates ...
• Synthesis of solution stable end-to-end linked gold nanorod dimers via pH-dependent surface reconfiguration 

  Kar, Ashish; Thambi, Varsha; Paital, Diptiranjan; Joshi, Gayatri; Khatua, Saumyakanti (American Chemical Society, 2020-07)

  End-to-end dimers of gold nanorods are predicted to be excellent substrates for surface-enhanced spectroscopy. However, synthesis of solution-stable end-to-end dimers remains challenging. Here we exploit the pH-dependent ...
• Synthesis and characterization of quinoline-3-carboxamide derivatives as inhibitors of the ATM kinase 

  Ravi, Srimadhavi; Barui, Sugata; Kirubakaran, Sivapriya; Duhan, Parul; Bhowmik, Kaushik (Bentham Science Publishers, 2020-07)

  Background: The importance of inhibiting the kinases of the DDR pathway for radiosensitizing cancer cells is well established. Cancer cells exploit these kinases for their survival which leads to the development of resistance ...
• In situ modulation of gold nanorod's surface charge drives the growth of end-to-end assemblies from dimers to large networks that enhance single-molecule fluorescence by 10?000-fold 

  Kar, Ashish; Thambi, Varsha; Paital, Diptiranjan; Khatua, Saumyakanti (Royal Society of Chemistry, 2020-05)

  End-to-end assemblies of anisotropic plasmonic nanostructures with small nanogaps are of great interest as they create strong hot spots for enhancing weak fluorescence and/or scattering of molecules. Here we report the ...
• A green route for beneficiation of metallic materials from electronic waste for selective reduction of CO2 

  Sharma, Nidhi; Bajpai, Anurag; Yadav, Pradeep Kumar; Nellaiappan, Subramanian; Sharma, Sudhanshu; Tiwary, Chandra Sekhar; Biswas, Krishanu (American Chemical Society, 2020-07)

  The effective disposal of ever-increasing electronic waste (e-waste) is one of the grand challenges for the scientific and technological community today. As e-waste has exponentially been increasing the burden on our ...
• Development and validation of the spectrophotometric method for the determination of menthol 

  Kushwah, H.; Hans, Tanya; Chauhan, M.; Mittal, G.; Sandal, N. (Springer Verlag, 2020-07)

  The main objective of the present study is a quantitative determination of menthol using a simple, sensitive, and reproducible method of reacting menthol with an aromatic aldehyde (salicylaldehyde) in an acidic medium. A ...
• Effect of Bi 3+ ion concentration on physicochemical, optical and catalytic properties of one?pot combustion synthesized nanocrystalline bi?doped La 2 O 3 

  Gangwar, Bhanu P.; Irusta, Silvia; Sharma, Sudhanshu (Wiley, 2020-07)

  La2?2xBi2xO3 (x=0?0.04) nanocrystalline powders are synthesized by one?pot single step solution combustion method. 4 atom% Bi doped La2O3 reveals the presence of both Bi3+ and metallic Bi. Temperature programmed reduction ...
• Live-cell imaging of lipid droplets using solvatochromic coumarin derivatives 

  Jana, Palash; Siva, Aravintha; Soppina, Virupakshi; Kanvah, Sriram (Royal Society of Chemistry, 2020-06)

  Lipid droplets (LDs), the lipid-rich intracellular organelles, serve to regulate many physiological processes and therefore attention has been attracted towards their selective detection. We report positively solvatochromic ...
• Superior resonant nanocavities engineering on photonic crystal-coupled emission platform for detection of femtomolar iodide and zeptomolar cortisol 

  Jana, Palash; Kanvah, Sriram et al. (American Chemical Society, 2020-06)

  Although luminescence spectroscopy has been a promising sensing technology with widespread applications in point-of-care diagnostics and chem-bio detection, it fundamentally suffers from low signal collection efficiency, ...
• Design and development of novel urea, sulfonyltriurea, and sulfonamide derivatives as potential inhibitors of sphingosine kinase 1 

  Roy, Sonam; Mahapatra, Amarjyoti Das; Mohammad, Taj; Gupta, Preeti; Alajmi, Mohamed F.; Hussain, Afzal; Rehman, Md. Tabish; Datta, Bhaskar; Hassan, Md. Imtaiyaz (MDPI, 2020-06)

  Sphingosine kinase 1 (SphK1) is one of the well-studied drug targets for cancer and inflammatory diseases. Recently discovered small-molecule inhibitors of SphK1 have been recommended in cancer therapeutics; however, ...
• The odyssey of cobaloximes for catalytic H2 production and their recent revival with enzyme-inspired design 

  Dolui, Dependu; Khandelwal, Shikha; Majumder, Piyali; Dutta, Arnab (Royal Society of Chemistry, 2020-06)

  Cobaloxime complex gained the attention for its intrinsic ability of catalytic H2 production, despite its initial emergence as a Vitamin B12 model. The simple, robust, and a synthetically manoeuvrable cobaloxime core ...
• Synthesis and characterization of a new class of phenothiazine molecules with 10H-substituted morpholine & piperidine derivatives: a structural insight 

  Hussain, Javeena; Angira, Deekshi; Hans, Tanya; Dubey, Pankaj; Kirubakaran, Sivapriya; Thiruvenkatam, Vijay (Elsevier, 2020-06)

  A series of 10H-substituted phenothiazine-based molecules were prepared by the base-catalyzed reactions. The synthesized compounds are characterized by Mass spectroscopy, NMR, and SCXRD to examine the role of different ...
• Synthesis of water-soluble thioglycosylated trans -A 2 B 2 type porphyrins: cellular uptake studies and photodynamic efficiency 

  Pandey, Vijayalakshmi; Raza, Md Kausar; Joshi, Pooja; Gupta, Iti (American Chemical Society, 2020-04)

  The synthesis of water-soluble thioglycosylated A2B2 type porphyrins and their zinc(II) complexes is reported. The water-soluble trans-A2B2 porphyrins were synthesized in two steps, via [2+2] condensation between ...
• Stereodivergent synthesis of 1-hydroxymethylpyrrolizidine alkaloids 

  Sarkale, Abhijeet M.; Appayee, Chandrakumar (American Chemical Society, 2020-05)

  A first stereodivergent strategy for the asymmetric synthesis of all stereoisomers of 1-hydroxymethylpyrrolizidine alkaloids is developed using an asymmetric self-Mannich reaction as a key step. An anti-selective self-Mannich ...
• Design, synthesis and biological evaluation of new Myo-inositol derivatives as potential RAS inhibitors 

  Hussain, Javeena; Chhabria, Dimple; Kirubakaran, Sivapriya (Elsevier, 2020-08)

  Ras is a small family of GTPases that control numerous cellular functions like cell proliferation, growth, survival, gene expression, and is closely engaged in cancer pathogenesis. The ras-targeted methodology entails a ...
• Synthesis, photophysical properties and computational studies of beta?substituted porphyrin dyads 

  Kesavan, Praseetha E; Pandey, Vijayalakshmi; Ishida, Masatoshi; Furuta, Hiroyuki; Mori, Shigeki; Gupta, Iti (Wiley, 2020-05)

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