• Insights into supramolecular assembly formation of diethyl aryl amino methylene malonate (DAM) derivatives assisted via non-covalent interactions 

  Shaik, Althaf; Angira, Deekshi; Thiruvenkatam, Vijay (Elsevier, 2019-05)

  The crystal structures of four derivatives of diethyl 2-(((aryl)amino)methylene)malonate (DAM) have been studied by single crystal X-ray diffraction. The molecular structures of all the four derivatives were found to be ...
• Inhibitors of Inosine 5´-monophosphate dehydrogenase as emerging new age antimicrobial agents 

  Juvale, Kapil; Shaik, Althaf; Kirubakaran, Sivapriya (Royal Society of Chemistry, 2019-05)

  Inosine 5´-monophosphate dehydrogenase (IMPDH) is a vital enzyme involved in the de-novo synthesis of guanine nucleotides. IMPDH catalyses a crucial step of converting IMP into XMP that is further converted into GMP. ...
• Hydrazide‐hydrazone small molecules as AIEgens: illuminating mitochondria in Cancer cells 

  Patil, Sohan; Pandey, Shalini; Singh, Amit; Radhakrishna, Mithun; Basu, Sudipta (Wiley, 2019-04)

  Aggregation induced emission probes (AIEgens) have gained lots of attention as interesting tools for ample biomedical applications especially bio-imaging due to their brightness and photo-stability. Numerous AIEgens have ...
• Synthesis and studies of phenothiazine based AIE fluorogens 

  Manav, Neha; Verma, Vani; Pandey, Vijayalakshmi; Rather, Hilal; Vasita, Rajesh; Gupta, Iti (NISCAIR-CSIR, 2019-02)

  Phenothiazine based AIE fluorogens linked to phenyl and tetraphenylethylene groups are reported. The N-butylphenothiazine and N-phenylphenothiazine have been substituted at 3,7-positions with phenyl or tetraphenylethylene ...
• Chemical method for evaluating catalytic turnover frequencies (TOF) of moderate to slow H2 oxidation electrocatalysts 

  Arnab Dutta; Wendy J. Shaw (American Chemical Society, 2019-06)

  Hydrogen has emerged as a long-term option for storing energy from renewable resources and has led the scientific community to develop enzyme-inspired catalysts for hydrogen oxidation and production. One of the most ...
• Catalytic regioselective ?-Methylenation of ?,?-Unsaturated aldehydes using formaldehyde via vinylogous aldol condensation 

  Kutwal, Mahesh S.; Dev, Sachin; Appayee, Chandrakumar (American Chemical Society, 2019-04)

  Formaldehyde is used as a one-carbon electrophile(1) in several organic transformations to functionalize aldehydes,(2) ketones,(3) amines,(4) and alkenes.(1c,5) However, the reaction of formaldehyde with α,β-unsaturated ...
• Adsorption of DNA bases on two?dimensional boron sheets 

  Sihag, Amita; Mallajosyula, Sairam Swaroop (Wiley, 2019-02)

  Utilizing two?dimensional (2D) sheets for DNA fingerprinting applications is an active field of research, with extensive research being carried out on graphene, h?BN and transition metal dichalcogenides. In this theoretical ...
• Novel pyrazolo [4, 3-c] quinolin-3-one derivatives as PDE5A inhibitors 

  Shaik, Althaf; Agarwal, Harshit Kumar; Bhakuni, Rashmi; Kirubakaran, Sivapriya (2019-02)

  Background: PDE5A is a phosphodiesterase which specifically hydrolyzes the cGMP to GMP. It takes part in several physiological and pathological pathways and is considered an important drug target. Currently, PDE5 inhibitors ...
• Branching effect on triphenylamine-CF3 cyanostilbenes: enhanced emission and aggregation in water 

  Kumari, Beena; Singh, Surya Pratap; Santosh, Ranga; Dutta, Arnab; Mallajosyula, Sairam Swaroop; Ghosal, Subhas; Kanvah, Sriram (Royal Society of Chemistry, 2019-03)

  Six linear and branched ?-cyanostilbene derivatives bearing a triphenylamine donor and an electron withdrawing trifluoromethyl group on the phenyl ring and a cyano acceptor on the double bond were synthesized and examined ...
• Small molecule fluorescent probes for G-Quadruplex visualization as potential cancer theranostic agents 

  Chilka, Pallavi; Desai, Nakshi; Datta, Bhaskar (2019-01)

  G-quadruplexes have gained prominence over the past two decades for their role in gene regulation, control of anti-tumour activity and ageing. The physiological relevance and significance of these non-canonical structures ...
• Polyethylenimine coated graphene-oxide nanoparticles for targeting mitochondria in cancer cells 

  Mallick, Abhik; Nandi, Aditi; Basu, Sudipta (American Chemical Society, 2018-12)

  Mitochondrion, the powerhouse of the cells, controls bioenergetics, biosynthesis, metabolism, and signaling. Consequently, it has become an unorthodox target for cancer therapeutics. However, specific targeting of mitochondria ...
• Emission and color tuning of cyanostilbenes and white light emission 

  Kumari, Beena; Paramasivam, Mahalingavelar; Dutta, Arnab; Kanvah, Sriram (American Chemical Society(ACS), 2018-12)

  White-light-emitting diodes are energy efficiency replacement of conventional lighting sources. Herein, we report the luminescent behavior of three simple cyanostilbenes with triphenylamine-donating groups bearing different ...
• La0.80Sr0.20CoO3 as a noble-metal-free catalyst for the direct oxidation of formic acid under zero applied potential 

  Bisht, Anuj; Pentyala, Phanikumar; Deshpande, Parag A.; Sharma, Sudhanshu (Elsevier, 2019-02)

  Direct oxidation of formic acid to CO2 using noble-metal-free La0.80Sr0.20CoO3 is demonstrated in this study. The catalyst was able to oxidize HCOOH without any externally applied potential. The activity of La0.80Sr0.20CoO3 ...
• Cationic red-emitting probes for the rapid and selective detection of SO2 derivatives in aqueous and cellular environments 

  Jana, Palash; Patel, Nishaben; Soppina, Virupakshi; Kanvah, Sriram (Royal Society of Chemistry (RSC), 2018-12)

  Two water-soluble compounds based on a coumarin–pyridinium scaffold were synthesized for rapid and selective detection of sulfite. The detection strategy is possible through a Michael addition reaction of the sulfite to ...
• Direct formic acid electro-oxidation on Pt Doped and Undoped La1-xSrxCoO3: activity suppression due to proton reduction reaction 

  Bisht, Anuj; Sharma, Sudhanshu (Electrochemical Society (ECS), 2018-10)

  Combustion synthesized Pt-doped and undoped La1-xSrxCoO3 are utilized for formic acid electro-oxidation. Cyclic-voltammetry (CV) during formic acid electro-oxidation demonstrates that the oxidation current initially increases ...
• Boron based nanosheets as reducing templates in aqueous solutions: towards novel nanohybrids with gold nanoparticles and graphene 

  James, Asha Liza; Khandelwal, Shikha; Dutta, Arnab; Jasuja, Kabeer (Royal Society of Chemistry, 2018-10)

  We show that nanosheets obtained by exfoliating magnesium diboride bear an intrinsic ability to elicit chemical reduction of quinone-based molecules. They also reduce gold salt into ultra-small gold nanoparticles and ...
• Evaluation of MBP tagged-hATR kinase domain catalytic activity with p53 Ser-15 phosphorylation 

  Bhakuni, Rashmi; Shaik, Althaf; Kirubakaran, Sivapriya (American Chemical Society, 2018-10)

  DNA damage response (DDR) pathways form an integral part of the body’s repair machinery, and ATR (ataxia-telangiectasia and Rad3-related kinase) protein is one of the key mediators in the DDR pathway that helps in maintaining ...
• Chemical method for evaluating catalytic turnover frequencies (TOF) of moderate to slow H2 oxidation electrocatalysts 

  Dutta, Arnab; Shaw, Wendy J. (American Chemical Society (ACS), 2018-10)

  Hydrogen has emerged as a long-term option for storing energy from renewable resources and has led the scientific community to develop enzyme-inspired catalysts for hydrogen oxidation and production. One of the most ...
• In search of the representative pharmacophore hypotheses of the enzymatic proteome of Plasmodium falciparum: a multicomplex-based approach 

  Manhas, Anu; Lone, Mohsin Y.; Jha, Prakash C. (Springer, 2018-10)

  Drug resistance has made malaria an untreatable disease and therefore intensified the need for the development of new drugs and the identification of potential drug targets. In this pursuit, in silico efforts made in the ...
• Cationic red emitting fluorophore: a light up NIR fluorescent probe for G4-DNA 

  Kumari, Beena; Yadav, Akanksha; Pany, Sushree P.; P. I., Pradeepkumar; Kanvah, Sriram (Elsevier, 2018-10)

  Guanine (G) quadruplexes (G4) are nucleic acid secondary structures formed by G-rich sequences, commonly found in human telomeric and oncogene-promoter regions, have emerged as targets for regulation of multiple biological ...

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